Rome, Italy – City Guide Situated in the Lazio region of central Italy is Rome. According to a legend, this capital city was founded by twin brothers Romulus and Remus. It is believed Romulus built the city next to the River Tiber in 753 BC and even though Rome has developed into a modern city with around 4 million inhabitants, it still maintains its historical legacy. Taking a walk through the streets of Rome will take you back in time – let Rome take you on this journey to discover the Colosseum, the magnificent Roman Squares and Vatican City. You won’t be disappointed. Enjoy a romantic break in Rome. Compare airfares and find cheap flights to Rome with eDreams.